To understand diseases, all layers of information need to be considered.
Applied Informatics to Research in Biomedical Science can be considered as a hierarchy ascending from:
For example, the following diagram shows how different type of data belong to the Bioinformatics and Health Informatics:
Source: The New Role of Biomedical Informatics in the Age of Digital Medicine
Research Areas of Informatics applied to Biomedical Science
Based on AMIA (American Medical Informatics Association), there are five major research areas of application of informatics to Biomedical Sciences. These are: